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(157) found that IF might improve cognitive function in elderly participants with mild cognitive impairment (MCI) through mechanisms such as antioxidant function, DNA damage, inflammation, and a limited set of metabolic biomarkers (insulin and HDL cholesterol)

Berberine and semaglutide is a popular combination that may have additive effects on blood sugar regulation but can also increase gastrointestinal side effects

Tsaousidou E, Paeger L, Belgardt BF, Pal M, Wunderlich CM, Brnneke H, Collienne U, Hampel B, Wunderlich FT, Schmidt-Supprian M, Kloppenburg P, Brning JC (2014) Distinct roles for JNK and IKK activation in Agouti-related peptide neurons in the development of obesity and insulin resistance

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